Investigation of the total and Short Form Patient Generated Subjective Global Assessment (Short Form PG-SGA) score as a screening tool in chemotherapy outpatients — ASN Events

Investigation of the total and Short Form Patient Generated Subjective Global Assessment (Short Form PG-SGA) score as a screening tool in chemotherapy outpatients (#445)

Jessica Abbott 1 2 , Laisa Teleni 3 , Daniel McKavanagh 1 , Jaimie Watson 1 , Alexandra McCarthy 1 4 , Elizabeth Isenring 1 3
  1. Princess Alexandra Hospital, Woolloongabba, QLD, Australia
  2. Gold Coast University Hospital, Southport, QLD, Australia
  3. Bond University, Robina, QLD, Australia
  4. Queensland University of Technology, Kelvin Grove, QLD, Australia

An abridged or Short Form PG-SGA score has recently been validated in the chemotherapy outpatient setting in place of the Malnutrition Screening Tool (MST) as a means of providing additional clinically relevant information during screening. The aim of this study was to identify the most relevant information contributing to the PG-SGA score to identify malnutrition with 80% sensitivity and 60% specificity. 

A cross-sectional study recruited patients actively receiving treatment in the oncology day unit. Patients self-administered the MST. A dietitian blinded to the MST score administered the PG-SGA. Receiver operating characteristic curves were generated to determine the optimal cut off scores of PG-SGA sections with the greatest sensitivity and specificity for predicting malnutrition according to SGA category.

300 participants were recruited (96.2% response rate), 51.7% male, 58.6±13.3yrs. Participants represented both solid tumours and haematological diagnoses. Scores calculated from weight (box 1), dietary intake (box 2) and symptom data (box 3) with or without activity/function (box 4) data were comparable (AUC=0.85, 95% CI=0.80-0.89; AUC=0.85, 95% CI=0.81-0.89, respectively) and had higher diagnostic value than the MST (AUC=0.77, 95% CI=0.72-0.82) or box 3 data alone (AUC=0.78, 95% CI=0.73-0.83). Using boxes 1-3, a PG-SGA score of ≥2 was 90% sensitive and 67% specific at identifying those at risk of malnutrition.

Although PG-SGA scores from boxes 1-4 had been validated previously, our study, with a larger sample and more diverse diagnoses, determined additional information provided by the functional capacity question did not improve the overall discriminatory value of the PG-SGA.

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