Geoff Lindeman, a clinician-scientist, is Joint Head of the Cancer Biology and Stem Cells Division at the Walter and Eliza Hall Institute. He is also a medical oncologist at the Peter MacCallum Cancer Centre and Royal Melbourne Hospital and holds an honorary appointment as Professorial Fellow in the Department of Medicine, University of Melbourne. He established the RMH Familial Cancer Centre and was inaugural Director of the Parkville Familial Cancer Centre. His group is interested in the molecular and cellular regulators of normal mammary gland development and changes that lead to hereditary and sporadic breast cancer. The discovery of RANK-positive progenitors as a target for breast cancer prevention in BRCA1 mutation carriers has led to the international breast cancer prevention trial, BRCA-P.