The Gut Microbiome and Gut Pathophysiology Groups are dynamic and innovative research laboratories in the School of Medical Sciences. The focus of our research is to investigate the toxic effects of anti-cancer therapies on the gastrointestinal tract and the development of clinically diagnosed diarrhoea (a manifestation of intestinal mucositis). Specific research foci centre on characterising the development of gastrointestinal toxicity in newly emerging anti-cancer drugs, and further characterising the pathogenesis. This novel research may also lead to the development of intervention agents to prevent or treat gastrointestinal toxicity and diarrhoea as well as novel platforms to study gastrointestinal toxicity. The group members have extensive experience in a variety of techniques and are widely published in fields including, pathology, molecular biology, microbiology and immunology. Their studies are supported by access to the research laboratories first-class facilities and a stimulating work environment.